在内神经外科手术后出现的新发性精神性非发作:元分析
Ruslan Akhmedullin1, Gaziz Kyrgyzbay2, Darkhan Kimadiev2
1Department of Medicine, Nazarbayev University School of Medicine, Kazakhstan.
Seizure
|May 18, 2024
概括
心理非发作 (PNES) 可能发生在内手术后,估计发生率为3%. 与其他手术相比,时间切除的风险更高,突出显示了脑外科手术对功能性发作流行病学的影响.
科学领域:
- 神经外科 神经外科
- 发病学 (Epileptology) 是一个专业的学科.
- 流行病学 流行病学
背景情况:
- 心理非发作 (PNES) 的流行病学仍然不太了解.
- 虽然每年有数百万人需要神经外科护理,但手术后PNES发生的数据有限.
- 这项研究旨在量化神经外科手术后新诊断的PNES的发病率.
研究的目的:
- 估计在内手术后患有精神性非发作 (PNES) 的患者比例.
- 为了研究特定的外科手术和PNES发病率之间的关联.
- 为了解神经外科手术对功能性发作障碍的影响作出贡献.
主要方法:
- 在主要数据库 (PubMed,Ovid,CINAHL,Cochrane) 进行了全面的文献搜索,截至2023年12月.
- 包括观察性研究报告的PNES发生在接受内外科手术的患者视频EEG确诊的诊断.
- 随机效应模型被用来组合比例,使用I2统计和Cochran的Q测试来评估异质性.
主要成果:
- 8项研究 (n=3,699) 符合纳入标准,主要关注1995年至2017年间的手术.
- 在内外科手术后,PNES的综合发病率为3% (95% CI 2%-5%).
- 与其他切除类型相比,切除与PNES风险增加两倍相关 (OR 2.05).
结论:
- 内手术似乎会影响功能性的流行病学,包括PNES.
- 需要进一步的研究来阐明各种大脑切除对PNES发病率的具体贡献.
- 了解这些关联可以为患者的护理和手术决策提供信息.
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