心率变化和中风或全身栓塞在心房的患者心率变化和中风或全身栓塞
Peter Hämmerle1, Stefanie Aeschbacher2, Vincent Schlageter2
1Cardiovascular Research Institute Basel, University Hospital Basel, University of Basel, Basel, Switzerland; Department of Cardiology, University Hospital Basel, University of Basel, Basel, Switzerland.
Heart rhythm
|May 18, 2024
概括
心脏自主功能受损,通过心率变化三角指数 (HRVI) 在鼻节律 (SR) 中测量,与心房动 (AF) 患者中风风险增加有关. 这一发现有助于改善AF患者中风风险分层.
科学领域:
- 心脏病学 心脏病学
- 自主神经系统研究 自主神经系统研究
- 临床电生理学 临床电生理学
背景情况:
- 心房动 (AF) 患者面临严重的中风风险,通常与自主神经系统障碍有关.
- 了解心脏自主功能与AF中风之间的联系对于风险管理至关重要.
研究的目的:
- 调查心脏自主功能受损是否与心房动患者中风风险更高相关.
- 测试将自主功能障碍与AF中风风险增加联系在一起的假设.
主要方法:
- 1922名AF患者 (1121名在鼻腔节律,801名在AF) 接受了5分钟的心电图记录.
- 计算了包括HRVI在内的心率变化 (HRV) 参数.
- 考克斯回归模型分析了HRV与中风/全身栓塞之间的关联.
主要成果:
- 在患有鼻节律 (SR) 的患者中,低HRVI (<15) 与中风/全身栓塞风险增加密切相关 (HR3.04,P=.009).
- 在AF组中,没有发现HRV参数与中风/全身栓塞之间的显著关联.
- 这项研究跟踪了1922名AF患者5年,观察中风/全身栓塞事件.
结论:
- 在鼻腔节律 (SR) 期间的心率变化三角指数 (HRVI) 独立预测AF患者中风或全身栓塞.
- 在短时间心电图记录上SR期间的HRV分析可以改善AF中风风险分层.
- 这表明SR期间自主功能评估对AF患者管理有价值.
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