围产期压力调节了谷氨基基功能连接:一个后突触密度立即早期基于基因的网络分析

Licia Vellucci1, Giuseppe De Simone2, Sara Morley-Fletcher3

  • 1Section of Psychiatry, Laboratory of Translational and Molecular Psychiatry and Unit of Treatment-Resistant Psychosis, Department of Neuroscience, Reproductive Sciences and Dentistry, University Medical School of Naples "Federico II", Naples, Italy; Department of Translational Medical Sciences, University of Naples "Federico II", Via S. Pansini 5, 80131 Naples, Italy.

概括

早期生活压力通过减少Homer1表达和破坏行为关键区域的网络,改变雄性大鼠的大脑连接. 这表明围产期压力和神经发育障碍模型之间存在联系.

相关概念视频

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Proteins can undergo many types of post-translational modifications, often in response to changes in their environment. These modifications play an important role in the function and stability of these proteins. Covalently linked molecules include functional groups, such as methyl, acetyl, and phosphate groups, and also small proteins, such as ubiquitin. There are around 200 different types of covalent regulators that have been identified.
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