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建立适当的中间终点的挑战和机会,反映患者的益处:非转移性前列腺癌研究和临床应用的路线图

Sabine D Brookman-May1, Marc Buyse2, Stephen J Freedland3

  • 1Department of Urology, Ludwig-Maximilians University Munich, Munich, Germany; Janssen Research and Development, Spring House, PA, USA.

European urology
|May 18, 2024
PubMed
概括

定义高风险前列腺癌的研究终点是困难的. 新的措施,如病理完整反应,可以更好地反映患者的益处,并减少治疗负担.

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Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...