认知作为肺功能和老年人中肉症风险的调解者
Zhao Hu1, Lu Tang2, Yiqiang Zhan3,4
1Department of Epidemiology, School of Public Health (Shenzhen), Sun Yat-Sen University, Shenzhen, China. huzh23@mail.sysu.edu.cn.
BMC public health
|May 18, 2024
概括
具有更好的肺功能的老年人患上沙尔科佩尼亚的风险较低. 虽然认知功能起着很小的作用,但其他因素可能与老年人的肺部健康和肌肉损失有关.
科学领域:
- 老年学是指老年学的学科.
- 肺部病理学 肺部病理学
- 老年病的医生 老年病的医生
背景情况:
- 老年人肺功能和肉症之间的联系尚不清楚.
- 随着年龄的增长而导致的肌肉损失萨尔科佩尼亚 (Sarcopenia) 带来了严重的健康风险.
研究的目的:
- 调查老年人肺功能和肉症之间的关联.
- 检查认知功能在这种关系中的调解作用.
主要方法:
- 分析了4011名中国老年人的全国代表性队列.
- 使用峰值呼气流 (PEF) 来评估肺功能.
- Sarcopenia 诊断遵循了 Sarcopenia (AWGS) 2019 年亚洲工作组的指导方针.
主要成果:
- 较高的PEF与显著降低患上皮症的风险相关 (HR:0.72).
- 每一个标准偏差增加的PEF与28%更低的肉类的风险相关.
- 认知功能部分调解了这种关联,占影响的12.2%.
结论:
- 肺功能受损是老年人中缩症的危险因素.
- 认知只能解释肺功能与肉症联系的很小一部分.
- 需要进一步的研究来确定连接肺功能和肉症的其他途径.
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