发生中风对晚年生活中的认知轨迹的影响
Swarna Vishwanath1,2, Ingrid Hopper1,3, Geoffrey C Cloud2,4
1School of Public Health and Preventive Medicine, Monash University, 553 St Kilda Road, Melbourne, VIC, 3004, Australia.
Alzheimer's research & therapy
|May 18, 2024
概括
脑卒中显著影响认知功能,导致记忆力和执行功能立即和长期下降. 早期的神经心理评估和干预对于中风幸存者来说至关重要,以管理认知变化.
科学领域:
- 神经学 神经学
- 神经科学是一个神经科学.
- 老年学是一门学科.
背景情况:
- 认知障碍和痴呆症是中风后的普遍结果.
- 评估中风前后认知能力的前性研究有限.
- 了解中风对老年人认知的影响至关重要.
研究的目的:
- 确定发生性中风对各种认知领域的影响.
- 分析老年社区居民在中风前后的纵向队列中的认知轨迹.
主要方法:
- 招募了19,114名没有先前心血管疾病或认知障碍的老年人.
- 监测参与者长达11年,判断事故中风 (缺血性和出血性).
- 使用修改型迷你心理状态检查 (3MS),HVLT-R,SDMT和COWAT评估认知,分析线性混合模型的变化.
主要成果:
- 815名参与者 (4.3%) 在平均8.4年的随访期间经历了中风.
- 脑卒中与3MS,HVLT-R,SDMT和COWAT分数的显著立即下降有关.
- 与对照组相比,3MS,COWAT和HVLT-R,但不是SDMT,在中风幸存者中观察到更的长期下降.
结论:
- 意外中风导致显著的,多方面的认知能力下降.
- 综合的神经心理评估对于中风后的监测至关重要.
- 早期干预策略可以减轻中风后的长期认知缺陷.
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