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Updated: Aug 9, 2026

Methods for the Modulation and Analysis of NF-κB-dependent Adult Neurogenesis
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抑制proBDNF到成熟的BDNF转化导致体内类似ASD的表型

Feng Yang1,2, He You2,3, Toshiyuki Mizui4

  • 1China National Clinical Research Center for Neurological Diseases, Basic and Translational Medicine Center, Beijing Tiantan Hospital, Capital Medical University, 100070, Beijing, China.

Molecular psychiatry
|May 18, 2024
PubMed
概括

在大脑中,亲脑衍生神经营养因子 (proBDNF) 转化为成熟的BDNF (mBDNF) 的改变会导致小鼠的自闭症谱系障碍 (ASD) 类行为. 血proBDNF/mBDNF比率的增加可能作为ASD生物标志物.

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