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Updated: Jun 26, 2025

Photodynamic Therapy with Blended Conducting Polymer/Fullerene Nanoparticle Photosensitizers
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Photodynamic Therapy with Blended Conducting Polymer/Fullerene Nanoparticle Photosensitizers

Published on: October 28, 2015

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用于低氧光动力学治疗的扭曲脊柱纯I型有机光敏剂的分子工程设计

Shiyang Liu1, Tianzhen Sun2, Wenxin Chou2

  • 1Key Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, No. 29 Zhongguancun East Road, Haidian District, Beijing, 100190, China; University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing, 100049, China.

European journal of medicinal chemistry
|May 19, 2024
PubMed
概括

研究人员开发了用于光动力学疗法 (PDT) 的新型I型光敏化剂 (PS). 这些PSs克服瘤缺氧,即使没有氧气,在摧毁癌细胞方面表现出高效率.

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相关概念视频

Photochemical Electrocyclic Reactions: Stereochemistry01:26

Photochemical Electrocyclic Reactions: Stereochemistry

The absorption of UV–visible light by conjugated systems causes the promotion of an electron from the ground state to the excited state. Consequently, photochemical electrocyclic reactions proceed via the excited-state HOMO rather than the ground-state HOMO. Since the ground- and excited-state HOMOs have different symmetries, the stereochemical outcome of electrocyclic reactions depends on the mode of activation; i.e., thermal or photochemical.
Selection Rules: Photochemical Activation
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DNA Topoisomerases02:02

DNA Topoisomerases

Topoisomerases are enzymes that relax overwound DNA molecules during various cell processes, including DNA replication and transcription. These enzymes regulate positive and negative DNA supercoiling without changing the nucleotide sequence. DNA overwinding in a clockwise direction results in positively supercoiled DNA, whereas underwinding in a counterclockwise direction produces negatively supercoiled DNA.
Types and Mechanism of action
Topoisomerases are divided into two main types. ...
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