相关实验视频

Updated: Jun 26, 2025

A Quantitative Measurement of Reactive Oxygen Species and Senescence-associated Secretory Phenotype in Normal Human Fibroblasts During Oncogene-induced Senescence
13:59

A Quantitative Measurement of Reactive Oxygen Species and Senescence-associated Secretory Phenotype in Normal Human Fibroblasts During Oncogene-induced Senescence

Published on: August 12, 2018

8.1K

聚烯纳米塑料暴露会通过Sirt1/ROS轴触发精子细胞衰老

Yuehui Liang1, Yurui Yang2, Chunsheng Lu3

  • 1School of Public Health, Wuhan University, Wuhan 430071, China.

Ecotoxicology and environmental safety
|May 19, 2024
PubMed
概括

聚烯纳米塑料 (PS-NPs) 暴露会通过通过p53-p21/Rb-p16通路和ROS诱导精子细胞衰老而导致男性生殖损伤. 固醇可以减轻这种损伤.

关键词:
氧化应激是一种氧化应激.聚乙烯纳米塑料的聚乙烯纳米塑料.聚乙烯 (Pterostilbene) 是一种制剂.生殖性毒性 生殖性毒性衰老是一种衰老.

更多相关视频

Evaluation of Injury-induced Senescence and In Vivo Reprogramming in the Skeletal Muscle09:14

Evaluation of Injury-induced Senescence and In Vivo Reprogramming in the Skeletal Muscle

Published on: October 26, 2017

9.6K
Mouse Round Spermatid Injection08:41

Mouse Round Spermatid Injection

Published on: January 26, 2024

716

相关概念视频

Spermatogenesis01:22

Spermatogenesis

Spermatogenesis is a complex process that involves the development of sperm cells from undifferentiated stem cells in the seminiferous tubules of the testes. The process is essential for the production of mature and functional sperm cells that are capable of fertilizing an egg.
The process of spermatogenesis can be divided into mitosis, meiosis, and spermiogenesis. During mitosis, the spermatogonia or stem cells divide to produce two identical daughter cells, type A and B spermatogonia. Type-A...
1.7K
Somatic to iPS Cell Reprogramming01:29

Somatic to iPS Cell Reprogramming

Reprogramming alters the gene expression in somatic cells, transforming them into induced pluripotent stem (iPS) cells over several generations. Scientists can reprogram cells by introducing genes for four transcription factors—Oct4, Sox2, Klf4, and c-Myc (OSKM) by viral or non-viral methods. These factors are also known as Yamanaka factors after Shinya Yamanaka, who first generated iPS cells using mouse skin cells. Yamanaka was awarded the Nobel Prize in Physiology or Medicine in 2012...
2.2K
Replicative Cell Senescence02:15

Replicative Cell Senescence

Replicative cell senescence is a property of cells that allows them to divide a finite number of times throughout the organism's lifespan while preventing excessive proliferation. Replicative senescence is associated with the gradual loss of the telomere — short, repetitive DNA sequences found at the end of the chromosomes. Telomeres are bound by a group of proteins to form a protective cap on the ends of chromosomes. Embryonic stem cells express telomerase — an enzyme that adds...
3.6K