在妊娠 trofhoblastic 疾病后使用避孕药:一个系统的审查
Jill M Hagey1, Kerry E Drury2, Samantha Kaplan3
1Division of Women's Community and Population Health, Department of Obstetrics and Gynecology, Duke University, Durham, NC, United States.
Contraception
|May 19, 2024
概括
荷尔蒙和非荷尔蒙避孕方法似乎对经过妊娠热性疾病 (GTD) 的患者来说是安全的. 它们不会影响β-人类胆性淋巴激素 (hCG) 缓解,也不会影响骨后妊娠 trofhoblastic 瘤 (GTN) 的风险.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 妇科瘤学 妇科瘤学
- 避孕药是一种避孕药,用于避孕.
背景情况:
- 妊娠热囊细胞疾病 (GTD) 需要谨慎管理,包括在监测期间有效的避孕措施,以防止未来怀孕.
- 各种避孕方法对GTD结局的安全性和影响,例如β-人类胆性腺激素 (hCG) 缓解和妊娠热囊细胞瘤 (GTN) 风险,需要系统评估.
研究的目的:
- 系统地审查避孕方法对妊娠 trofhoblastic 疾病 (GTD) 之后的关键结果的影响.
- 评估对β-人类胆性淋巴激素 (hCG) 缓解时间,骨后孕期热囊细胞瘤 (GTN) 风险和意外怀孕的影响.
- 研究避孕方法与GTD治疗 (如化疗) 之间的潜在相互作用.
主要方法:
- 在PubMed和其他数据库中进行了全面的文献搜索,截至2023年4月.
- 包括的研究包括随机对照试验,观察性研究和涉及使用避孕方法的GTD患者的病例报告.
- 数据提取的重点是β-hCG缓解,GTN风险,意外怀孕风险和避孕药治疗相互作用,并进行了质量评估.
主要成果:
- 在5105项已识别的研究中,包括了42项,评估了8294名参与者.
- 可获得的数据有限,但在不同类型避孕药的β-hCG监测,GTN风险或意外怀孕方面没有发现显著差异.
- 在避孕方法和针对癌症的全身治疗之间没有发现特定的相互作用或不良事件.
结论:
- 根据GTD,荷尔蒙和非荷尔蒙避孕方法都被认为是安全的.
- 在全方位的避孕方案上为患者提供咨询对生殖健康和尽量减少疾病进展风险至关重要.
- 使用避孕药似乎不会改变hCG回归或后GTN的风险.
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