在为膀癌进行激进囊切除术的患者中,社会脆弱性和接受新辅助化疗
Rishi R Sekar1, Sarosh Irani2, Avinash Maganty2
1Department of Urology, University of Michigan, Ann Arbor, MI; National Clinician Scholars Program, University of Michigan, Ann Arbor, MI.
Urology
|May 19, 2024
概括
社会脆弱性与肌肉侵入性膀癌 (MIBC) 的新辅助化疗较少相关. 识别弱势患者可以改善公平的膀癌症护理.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 医疗保健服务研究 医疗服务研究
背景情况:
- 健康的社会决定因素对癌症护理的提供和结果产生重大影响.
- 社会脆弱性指数 (SVI) 是衡量人口层面不利状况的工具.
- 了解癌症治疗中的差异对于改善患者公平至关重要.
研究的目的:
- 评估CDC SVI与肌肉侵入性膀癌 (MIBC) 患者接受新辅助化疗之间的关联.
- 调查不同SVI子主题与化疗利用的关系.
- 为了确定在脆弱人群中公平治疗癌症的潜在障碍.
主要方法:
- 对978名非转移性MIBC患者进行了回顾性分析,这些患者接受了激进囊切除术 (2000-2022年).
- 根据邮政编码将患者分为SVI五分之一.
- 用于分析SVI和化疗协会的多变量逻辑回归,对共变量进行调整.
主要成果:
- 50.1%的患者接受了新辅助化疗.
- 较高的SVI与接受化疗的几率较低相关 (OR 0.61).
- 社会经济地位和家庭组成/残疾子主题显示与接受化疗有类似的负面关联.
结论:
- 社会脆弱性与MIBC患者新辅助化疗使用的差异有关.
- 需要针对弱势群体进行有针对性的干预,以提高膀癌治疗的公平性.
- 解决健康的社会决定因素对于公平的瘤结果至关重要.
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