干眼疾病和喉回流的相关性基于联合治疗改善的症状
Xiaoyu Wang1, Tingting Wu2, Zhi Liu1
1Department of Otolaryngology, The Sixth Medical Center of PLA General Hospital of Beijing, Beijing, Beijing 100048, China.
概括
干眼病 (DED) 和喉回流 (LPR) 有关. 同时治疗这两种疾病,特别是使用组合疗法,对患有DED和LPR症状的患者显示出更好的结果.
科学领域:
- 眼科医生 眼科 眼科
- 胃肠病学 胃肠病学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 干眼病 (DED) 和喉回流 (LPR) 是常见的疾病.
- DED和LPR之间的关系需要进一步研究,特别是关于治疗疗效.
研究的目的:
- 探索DED和LPR之间的相关性.
- 评估患有同时存在DED和LPR的患者的治疗反应.
主要方法:
- 在AIER眼科医院对219名患者进行了横截面研究.
- 利用眼表面症状指数 (OSDI) 和反流症状得分 (RSS) 来诊断DED和LPR.
- 患有这两种疾病的患者被随机分配到三个治疗组进行3个月的随访.
主要成果:
- 与LPR阴性患者相比,LPR患者的OSDI得分显著更高 (P < 0.001).
- 组合治疗组 (B组) 与仅服用眼滴或口服药物 (P < 0.001) 的组相比,DED和LPR参数的改善显著更大 (P < 0.001).
结论:
- 在LPR和DED之间存在强烈的相关性.
- 同时治疗LPR和DED似乎是一个更有效的治疗策略.
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