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Updated: Jun 26, 2025

A Murine Cell Line Based Model of Chronic CDK9 Inhibition to Study Widespread Non-Genetic Transcriptional Elongation Defects TEdeff in Cancers
10:49

A Murine Cell Line Based Model of Chronic CDK9 Inhibition to Study Widespread Non-Genetic Transcriptional Elongation Defects TEdeff in Cancers

Published on: September 26, 2019

5.6K

DEPDC5通过限制mTORC1-介导的纯氨酸代谢来保护CD8+ T细胞免受铁亡

Song Li1,2, Xinxing Ouyang1,3, Hongxiang Sun1,2

  • 1Shanghai Institute of Immunology, Department of Immunology and Microbiology at Basic Medical College, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Cell discovery
|May 19, 2024
PubMed
概括

在患者中,DEPDC5蛋白质损失会减少CD8+ T细胞,并降低抗瘤免疫力. 这项研究揭示了DEPDC5保护CD8+T细胞免受铁亡,提供了促进癌症免疫力的新策略.

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Assessing the Development of Murine Plasmacytoid Dendritic Cells in Peyer's Patches Using Adoptive Transfer of Hematopoietic Progenitors13:34

Assessing the Development of Murine Plasmacytoid Dendritic Cells in Peyer's Patches Using Adoptive Transfer of Hematopoietic Progenitors

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