在瑞典,在患有医疗疾病的成年人中治疗酒精使用障碍的药物治疗
Anastasia Månsson1, Anna-Karin Danielsson2, Hugo Sjöqvist2
1Department of Global Public Health, Karolinska Institutet, Stockholm, 171 77, Sweden. anastasia.mansson@ki.se.
Addiction science & clinical practice
|May 19, 2024
概括
患有酒精使用障碍 (AUD) 和其他疾病的患者不太可能接受AUD药物. 药物治疗的不足利用表明需要改善这些复杂患者的治疗机会.
科学领域:
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
- 胃肠病学 胃肠病学
背景情况:
- 酒精使用障碍 (AUD) 经常与其他医疗条件同时发生.
- 对AUD的药理疗法可用,但在伴随疾病的患者中未得到充分利用.
- 需要对AUD药物治疗处方模式进行研究,用于同时出现诊断的患者.
研究的目的:
- 调查AUD药理疗法 (阿卡姆普罗沙特,迪苏尔菲拉姆,纳尔特雷) 在专业护理中的使用情况.
- 为了检查患有AUD和并发性医学诊断的患者的处方率.
主要方法:
- 瑞典一项针对132,728名在2007年至2015年期间被诊断患有AUD的成年人的全国性队列研究.
- 在AUD诊断后12个月内对AUD药物治疗的处方数据的分析.
- 使用混合效应逻辑回归来计算基于并发性疾病的处方接收几率比率.
主要成果:
- 患有酒精相关的医学诊断的个人接受AUD药物治疗的几率明显降低.
- 心血管,神经和胃肠道疾病与最低的处方率有关.
- 药物治疗的禁忌不能完全解释观察到的使用不足.
结论:
- 在患有并发性医疗疾病的患者中,AUD药物治疗的使用不足.
- 对这一群体增加药物治疗的提供对于预防发病率和死亡率至关重要.
- 需要进一步的研究,以了解患者和处方者对AUD药物的障碍.
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