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国际时间趋势和局部行动性角质炎治疗利用率的差异
Heather J Zhao1,2, Inna Ushcatz1,2, Mina Tadrous1,3
1Department of Medicine, Women's College Research Institute, Women's College Hospital, Toronto, Ontario, Canada.
JAAD international
|May 20, 2024
概括
与中等收入国家相比,高收入国家使用的治疗方法显著更多的局部治疗 Actinic Keratoses (AK),一种癌前皮肤疾病. 这项研究突出了全球在AK治疗获得和经济相关性方面的差异.
科学领域:
- 皮肤病学 皮肤病学
- 药物经济学 药物经济学
- 全球健康 全球健康
背景情况:
- 行动性角质瘤 (AK) 被认为是癌前病变,有可能发展为状细胞癌.
- 在AK治疗局部药物的应用方面存在显著的国际差异,这些差异仍未得到充分记录.
研究的目的:
- 为了划分全球在使用局部药物的差异用于Actinic Keratoses.
- 调查一个国家的经济状况与其AK局部治疗的使用模式之间的关系.
主要方法:
- 分析IQVIA MIDAS药品销售数据,涵盖2011年4月至2021年12月的65个国家 (42个高收入国家,24个中等收入国家).
- 计算每个国家每1000人每季度使用药物的数量,以克为单位.
- 应用单变量线性回归来检查国家经济地位与AK药物使用之间的关联.
主要成果:
- 高收入国家表现出更高的利用率:15.37g/1000人口对5-甲,4.64g/1000人口对伊米奎莫德,和0.32g/1000人口对英甲酸.
- 在高收入和中等收入国家之间,在消费关键的局部AK治疗中观察到有统计学意义的差异.
结论:
- 研究结果表明,与中等收入国家相比,高收入国家局部行动性角质瘤治疗使用增加的明显趋势.
- 经济因素似乎在全球范围内对局部AK治疗的差异性获取和使用中发挥了作用.
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