叠加方法 质子抑制剂/Nux vomica-Heel作为胃食道逆流管理的新干预措施:德尔菲共识研究
Edda Battaglia1, Luciano Bertolusso2, Marco Del Prete3
1Gastroenterology Unit, ASLTO4, Ivrea 10015, Turin, Italy. edda.battaglia@gmail.com.
World journal of gastroenterology
|May 20, 2024
概括
胃食道逆流性疾病 (GERD) 可以通过使用质子抑制剂 (PPI) 和Nux vomica-Heel的重叠方法来管理. 这种共识表明,Nux vomica-Heel有助于减少PPI的依赖和保持症状控制.
科学领域:
- 胃肠病学 胃肠病学
- 药理学 药理学是指药理学的学科.
- 基于证据的医学是基于证据的医学.
背景情况:
- 胃食道逆流性疾病 (GERD) 影响了高达20%的西方人口.
- 目前的GERD治疗方法,如质子抑制剂 (PPI),由于潜在的不良影响,需要谨慎管理.
- 需要安全有效的替代药理选择来治疗GERD.
研究的目的:
- 通过共识过程优化GERD诊断和治疗指南.
- 评估一个重叠的治疗模式,将PPI与Nux vomica-Heel结合起来治疗GERD.
- 建立关于GERD管理的新干预模式的共识.
主要方法:
- 一个经过修改的德尔菲过程,涉及49名意大利医疗专家,跨越各个学科.
- 文献分析和两轮在线问卷以收集专家意见.
- 专注于两个主要领域:GERD疾病特征和GERD治疗策略.
主要成果:
- 在所有15个关于GERD疾病和治疗的评估陈述中达成一致共识.
- 专家之间达成高度一致 (疾病70-92%,治疗90-100%)
- 强烈支持采用与PPI和Nux vomica-Heel作为新的GERD管理模式的重叠方法.
结论:
- Nux vomica-Heel为GERD治疗提供了一个可行的选择.
- 这种方法支持PPI的抑郁,同时保持疾病控制和症状缓解.
- 共识强调了关于Nux vomica-Heel作为GERD的新干预措施的独特协议.
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