胃癌风险因素的热点和趋势:可视化和文献计量分析
Meng Li1, Ning Gao2, Shao-Li Wang3
1Department of Gastroenterology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China. zyxyjslm@163.com.
World journal of gastrointestinal oncology
|May 20, 2024
概括
识别胃癌 (GC) 风险因素,如Helicobacter pylori感染和遗传因素,对于早期诊断至关重要. 这项研究强调了GC风险因素识别的关键领域和新兴趋势.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 生物信息学是一种生物信息学.
背景情况:
- 由于非特异性症状,胃癌 (GC) 诊断具有挑战性.
- 识别GC风险因素对于早期检测和改善生存率至关重要.
- 本研究旨在绘制研究趋势和GC的关键风险因素.
研究的目的:
- 确定有关胃癌风险因素的不断变化的研究趋势和热点.
- 构建一个重要的GC风险因素的综合清单.
- 为早期识别高风险GC患者提供参考.
主要方法:
- 从Web of Science核心集合中对2514篇研究文章进行了图书统计分析.
- 使用CiteSpace V和VOSviewer 1.6.18进行文献分析.
- 选并提取有关GC风险因素的相关信息.
主要成果:
- 确定中国是最具生产力的国家,国家癌症中心是主要机构.
- 研究热点包括Helicobacter pylori (H. pylori) 感染,单核酸多态 (SNP),生物诊断标记物和GC风险预测模型.
- 杆菌感染和SNP成为显著的风险因素,生物诊断标志物显示出有前途.
结论:
- 杆菌感染是GC的主要危险因素.
- 单核酸多态性 (SNP) 是最重要的遗传风险因素.
- 新兴研究重点关注GC风险预测模型,其中H. pylori感染,SNP,吸烟,饮食和酒精是关键因素.
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