在患有转移性胃癌的患者中,萨尔科佩尼亚对生存有效吗?
Ozlem Dogan1, Hayriye Sahinli2, Yakup Duzkopru2
1Department of Medical Oncology, Adıyaman University Training and Research Hospital, Adiyaman 02100, Turkey. drozlemdogan@hotmail.com.
World journal of gastrointestinal oncology
|May 20, 2024
概括
肉,肌肉质量的损失,显著降低了转移性胃癌患者的生存率. 通过CT扫描和营养支持的早期识别可能会改善结果.
科学领域:
- 在瘤学瘤学.
- 老年病的医生 老年病的医生
- 放射学 放射学是一门学科.
背景情况:
- 标志着肌肉质量和密度降低的萨尔科佩尼亚在固体器官恶性瘤中很常见.
- 了解萨科佩尼的影响对于治疗癌症患者至关重要.
研究的目的:
- 评估萨科佩尼亚对转移性胃癌患者整体生存时间的影响.
- 为了确定 sarcopenia 和生存率之间的相关性.
主要方法:
- 对118名转移性胃癌患者 (2008-2020) 的回顾性分析.
- 使用从诊断CT扫描中平均的Hounsfield单位 (HUAC) 来评估肉症.
- 麻症状况与患者生存数据的相关性.
主要成果:
- 在24.6% (29/118) 的患者中出现了肉类.
- 与非sarcopenic患者 (10个月) 相比,sarcopenic患者 (2个月) 的中位生存时间明显较低.
- 在萨科佩尼亚和生存率之间发现了统计学上显著的关联 (P < 0.001).
结论:
- 萨尔科佩尼亚对转移性胃癌的存活率产生负面影响.
- 来自CT扫描的HUAC测量提供了一种快速,廉价的方法来识别sarcopenia.
- 营养支持可能会改善sarcopenic癌症患者的生存结果.
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