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炎症性肠病的不同表现基于种族和移民身份
Ali Khalessi1, Brooks R Crowe1, Yuhe Xia2
1Department of Medicine, New York University School of Medicine, New York, New York.
Gastro hep advances
|May 20, 2024
概括
炎症性肠病 (IBD) 的表现因种族和移民身份而异. 外国出生的患者通常会经历较轻的疾病,发病时间较晚,影响预后和管理策略.
科学领域:
- 胃肠病学 胃肠病学
- 流行病学 流行病学
- 免疫学 免疫学 免疫学
背景情况:
- 全球炎症性肠病 (IBD) 患病率的增加需要了解严重疾病的风险因素.
- 种族/种族和移民身份是IBD表现和结果的潜在决定因素.
- 三级医疗保健安全网医院为多样化的患者群体提供服务,提供独特的见解.
研究的目的:
- 调查种族/种族和移民身份对IBD的影响.
- 根据这些人口因素分析IBD发病,治疗和结果的变化.
- 在不同的人群中为IBD的临床管理和预后提供信息.
主要方法:
- 从1997年至2017年,对577名IBD患者 (住院患者和门诊患者) 的回顾性评估.
- 后勤回归建模用于根据种族 (白人,黑人,西班牙裔,亚洲人) 和移民身份 (美国出生的与外国出生的) 进行疾病特征比较.
- 对疾病发病,治疗方法和临床结果的分析.
主要成果:
- 亚洲患者更有可能是男性;与白人相比,黑人患者的克罗恩病和肠切除率更高.
- 外国出生的患者更有可能患有性结肠炎,并且不太可能患有早期发病,肠切除或接受生物药物.
- 观察到IBD表型,治疗和结果在种族/族群之间以及在美国出生的和外国出生的个人之间存在显著差异.
结论:
- IBD表型表现出基于种族/种族的显著变化.
- 外国出生的患者,不论种族,往往出现晚发和较轻的疾病.
- 这些发现有助于理解IBD的发病过程,并为个性化临床管理策略提供信息.
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