在坦桑尼亚,2019年至2023年间,用于治疗勃起功能障碍的5型固酶抑制剂的利用趋势
Raphael Z Sangeda1, Auleria W Kadinde1, Cassian F Masatu2
1Pharmaceutical Microbiology, Muhimbili University of Health and Allied Sciences, Dar es Salaam, TZA.
在坦桑尼亚,用于治疗勃起功能障碍 (ED) 的基化酶类型-5抑制剂 (PDE5I) 的使用正在增加. 西尔德纳菲尔是最常用的PDE5阻断剂,强调需要监督以确保适当使用并最大限度地降低风险.
科学领域:
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
背景情况:
- 勃起功能障碍 (ED) 显著影响全球健康和生活质量.
- 固酶-5型抑制剂 (PDE5I) 是ED的主要治疗方法.
- 了解PDE5I利用模式对于公共卫生管理至关重要.
研究的目的:
- 分析从2019年到2023年在坦桑尼亚使用PDE5Is的趋势.
- 为了确定最常用的PDE5I及其品牌.
- 预测PDE5Is的未来使用模式.
主要方法:
- 使用坦桑尼亚药品和医疗器械管理局 (TMDA) 的进口数据进行了回顾性纵向研究.
- 数据分析包括微软Power BI用于可视化和IBM SPSS用于统计分析.
- 使用趋势使用曲线拟合,霍尔特线性趋势模型和ARIMA模型进行评估,计算每1000名居民每日定义剂量 (DID).
主要成果:
- 观察到PDE5I进口的显著增加,在2019年至2023年期间大约有587个货物.
- 霍尔特的模型预测DID从2019年的0.220910上升到2025年的0.534272 (R平方=0.843).
- 西尔德纳菲尔占总使用量的75.5%,而Erecto是消费量最多的品牌 (37.6%的DID总量). 2022年出现了最高的激增 (27.2%).
结论:
- 坦桑尼亚的PDE5抑制剂的年度使用趋势显示出持续增长.
- 这些发现强调了对适当的PDE5I使用的批判性监督和有效政策的需要.
- 鉴于使用模式的上升,风险最小化策略至关重要.
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