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Updated: Jun 26, 2025

Identification of Protein Complexes in Escherichia coli using Sequential Peptide Affinity Purification in Combination with Tandem Mass Spectrometry
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Identification of Protein Complexes in Escherichia coli using Sequential Peptide Affinity Purification in Combination with Tandem Mass Spectrometry

Published on: November 12, 2012

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细菌50S组件中的域巩固由反感性寡核酸探测揭示

Kai Sheng1, Xiyu Dong1, Sriram Aiyer2

  • 1Department of Integrative Structural and Computational Biology, Department of Chemistry, and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.

bioRxiv : the preprint server for biology
|May 20, 2024
PubMed
概括

研究人员使用反感官寡核酸 (ASO) 发现了细菌核糖体组装中的新中间结构. 这揭示了大型RNA-蛋白质复合体 (RNP) 的分层,模板导向的折叠过程.

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相关概念视频

Ribosome Profiling02:24

Ribosome Profiling

Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique...
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