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Updated: Jun 26, 2025

Generation of CAR T Cells for Adoptive Therapy in the Context of Glioblastoma Standard of Care
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Generation of CAR T Cells for Adoptive Therapy in the Context of Glioblastoma Standard of Care

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葡萄糖载体5增强CAR-T细胞代谢功能和抗瘤耐用性

Bakir Valentić1,2, Andre Kelly1,2, Alexander A Shestov1,2

  • 1Center for Cellular Immunotherapies, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.

Research square
|May 20, 2024
PubMed
概括

工程 GLUT5 通过利用果糖来增强 CAR-T 细胞的抗瘤功能,改善代谢适应性并克服瘤微环境中的葡萄糖耗尽.

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