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一个实时的生物化学测试,用于对APOBEC催化DNA除的定量分析

Christopher A Belica1,2,3, Michael A Carpenter4,5, Yanjun Chen4

  • 1Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA, 55455.

bioRxiv : the preprint server for biology
|May 20, 2024
PubMed
概括

研究人员开发了一种新的检测方法来检测APOBEC3介导的DNA去胺. 这种工具有助于发现癌症突变发生抑制剂,提供了一种敏感且可扩展的方法.

关键词:
在 APOBEC3 中,APOBEC3 是生物技术是生物技术.癌症 癌症 癌症 癌症 癌症赛蒂丁脱胺酶的作用光共振能量转移 (FRET) 是一种高通量选 (HTS) 是一种高通量选.突变发生的突变发生.蛋白质-DNA相互作用实时测试实时测试身体突变 - 身体突变

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