对于非结核性菌根性肺病的辅助手术切除:有效性和并发症
Ji Yong Kim1, Jae Kwang Yun1, Geon Dong Lee1
1Department of Thoracic and Cardiovascular Surgery, Division of Thoracic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Annals of thoracic medicine
|May 20, 2024
概括
当抗生素失败时,肺切除为非结核菌肺病 (NTMPD) 提供了一种可行的治疗方法. 仔细选择患者是管理风险和改善NTMPD手术结果的关键.
科学领域:
- 肺部医学 肺部医学
- 胸部外科手术 胸部外科手术
- 传染性疾病 传染性疾病
背景情况:
- 对于非结核菌肺病 (NTMPD) 的标准抗生素治疗产生了低于最佳的结果.
- 肺切除是耐火性NTMPD的辅助,但缺乏明确的外科手术指南.
- 本研究评估了NTMPD的手术结果和风险因素.
研究的目的:
- 评估肺切除在治疗NTMPD中的疗效.
- 为了确定与NTMPD手术后不良结果相关的风险因素.
- 提供关于在NTMPD中进行手术干预的患者选择的见解.
主要方法:
- 从2007年至2021年对医疗记录的回顾性分析.
- 包括71名经过胸部手术的NTMPD患者.
- 对临床,微生物学和手术结果的分析,包括风险因素评估.
主要成果:
- 肺切除在73.9%的患者中实现了负的酸快菌根 (AFB) 培养转化.
- 在55.1%的病例中观察到长期持续的负转换.
- 复发的风险因素包括年龄较大,男性性别和广泛的疾病;间歇性肺病和肺切除术增加了死亡风险.
结论:
- 肺切除是NTMPD的有效辅助疗法,特别是在与术后抗生素相结合时.
- 由于潜在的并发症和复发,仔细选择患者至关重要.
- 了解年龄,并发症和疾病程度等风险因素可以改善NTMPD的手术决策.
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