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Updated: Jun 26, 2025

Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms
09:51

Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms

Published on: May 25, 2018

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工程微型CRISPR-Cas Un1Cas12f1用于高效的基础编辑.

Yueer Hu1, Linxiao Han1, Qiqin Mo1

  • 1Gene Editing Center, School of Life Science and Technology, ShanghaiTech University, Shanghai, China.

Molecular therapy. Nucleic acids
|May 20, 2024
PubMed
概括

新的微型基础编辑器 (STUminiBEs) 克服了基因治疗的腺相关病毒载荷限制. 这些超紧的编辑器实现了A-to-G和C-to-T转换的高效率,从而实现了潜在的生物医学应用.

关键词:
在 AAV AAV AAV 中.MT:RNA/DNA编辑 编辑这就是Sso7d.在Un1Cas12f1中基础编辑 基础编辑这是一个微型的CRISPR.蛋白质工程工程 蛋白质工程

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