对心房动进行DC心脏转换后的抗心律偏好和结果,澳大利亚农村视角
Martin Thomas1,2, James Elhindi3, Kanishka Kamaladasa1
1Department of Cardiology, Dubbo Base Hospital, Dubbo, New South Wales, Australia.
The Australian journal of rural health
|May 20, 2024
概括
在澳大利亚农村地区,阿米奥达龙,索塔洛尔和没有抗失常药物 (AAD) 在对心房动 (AF) 进行直流心转动 (DCCV) 后维持鼻节律方面表现出类似的适度疗效. 处方做法各不相同,在这种环境中优先考虑安全.
科学领域:
- 心脏病学 心脏病学
- 药理学 药理学是指药理学的学科.
背景情况:
- 直流心转 (DCCV) 是对症状性心房动 (AF) 的推治疗方法.
- 抗节律药物 (AAD) 常常在DCCV后被处方,以维持鼻节律 (SR).
- 关于澳大利亚农村环境中AAD处方模式和疗效的数据有限.
研究的目的:
- 为了确定DCCV后的首选AAD和影响因素.
- 评估AADs在DCCV后12个月内维持SR的疗效.
主要方法:
- 对233名非膜AF患者进行了回顾性观察审计,这些患者接受了DCCV.
- 在澳大利亚新南威尔士州的一家区域医院进行的研究 (2015-2020).
- 在DCCV后12个月的随访.
主要成果:
- 艾米奥达龙是最受欢迎的AAD,其次是索塔醇和弗莱卡因尼德.
- 35.2%的患者没有接受DCCV后的AAD.
- 阿米奥达龙,索塔醇和没有AAD在维持SR方面表现出类似的适度疗效 (AF复发率:分别为61.5%,68.2%,71.6%).
- 影响AAD处方的因素包括脑血管事故,肺部疾病,吸烟和左心室功能障碍.
结论:
- 在维护DCCV后12个月的SR方面,在阿米奥达龙,索塔醇和没有AAD之间没有观察到有效性的显著差异.
- 在这种农村环境中,AAD的处方做法与国家趋势和指导方针有所不同.
- 对AAD处方需要采取多方面的方法,优先考虑安全,并考虑农村医疗保健的挑战.
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