改善了PISA-DIA使用扩展,重叠温度梯度的药物向解卷

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Updated: Jun 26, 2025

Author Spotlight: Quantification of Complex Lipidomic Samples Using Stable Isotope Labeling
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Author Spotlight: Quantification of Complex Lipidomic Samples Using Stable Isotope Labeling

Published on: August 23, 2024

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Samantha J Emery-Corbin1,2, Jumana M Yousef1,2, Subash Adhikari1,2

  • 1Advanced Technology and Biology Division, the Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.

Proteomics
|May 20, 2024
PubMed
概括

我们通过无标签的DIA (PISA-DIA) 方法开发了一种新的蛋白质组整体溶解性改变,用于药物向解卷. 这种方法提高了蛋白质组的覆盖范围和灵敏度,改善了新型化合物的标识.

关键词:
蛋白质组整体溶解度变化数据的独立获取 (DIA)质谱测量质谱测量质谱测量质谱测量质量测量质谱测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量蛋白质的稳定性 蛋白质的稳定性蛋白质组学 蛋白质组学目标参与度 目标参与度热蛋白质组的概况分析

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