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个性化传统中医治疗反复性尿路感染的抗生素:一个多中心的随机对照研究
G U Xiangchen1, Qiu Meisi2,1, Xie Lin1
1Department of Nephrology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China.
个性化中医药有效地减少了女性的反复性尿路感染 (rUTIs). 这种方法改善了生活质量,增强了免疫力,为抗生素提供了替代品,并有助于预防抗生素耐药性.
科学领域:
- 综合医学是一个整体医学.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 药理学 药理学是指药理学的学科.
背景情况:
- 经常性尿路感染 (rUTIs) 显著影响女性的健康.
- 长期抗生素预防是常见的,但引起了人们对抗生素耐药性的担忧.
- 个性化中医药为管理RUTI提供了一个潜在的替代方案.
研究的目的:
- 系统地评估个性化中医药在预防RUTI复发方面的疗效.
- 为了比较个性化中医药与标准抗生素治疗在RUTIs的缓解阶段的影响.
主要方法:
- 一项随机对照试验,涉及230名成年女性患者,他们患有缓解的RUTIs.
- 患者根据综合征差异化或安慰剂的抗生素治疗接受了个性化的中国草药.
- 测量结果包括尿路感染复发率,传统中医 (TCM) 综合征得分,SF-36生活质量和尿液分泌免疫球蛋白A (SIgA).
主要成果:
- 与对照组相比,个性化中医组的短期和长期尿路感染复发率明显较低.
- 在中医药组中,TCM综合征得分和SF-36生活质量有显著的改善.
- 在接受个人化中医治疗的患者中,尿液SIgA水平显著增加.
结论:
- 个性化中医药在缓解期间有效减少RUTI复发.
- 这种治疗方法改善了患者的生活质量,并增强了免疫功能 (尿液SIgA).
- 综合症差异化中医提供了一种有前途的策略,以对抗抗生素耐药性在RUTI管理.
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