评估终身体育活动与口腔状细胞癌之间的关联:一项病例对照研究
Seyyed Abolfazl Tabatabaie-Zadeh1, Nazanin Mahdavi2, Behnaz Mahdaviani3
1School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
PloS one
|May 20, 2024
概括
终身体育活动所花费的总时间可能会降低口腔状细胞癌的风险. 然而,整体身体活动水平和强度与口腔癌风险没有显著关联.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 口腔癌对全球健康构成重大负担,口腔状细胞癌 (OSCC) 是主要的类型.
- 了解可修改的风险因素,如身体活动,对于OSCC预防策略至关重要.
研究的目的:
- 研究终身体育活动水平与患口腔状细胞癌的风险之间的关联.
主要方法:
- 一项涉及100名OSCC患者和200名健康对照者的病例控制研究.
- 使用终身体育活动问卷评估的终身体育活动,涵盖职业,家庭和体育领域.
- 用于性别,年龄,吸烟和饮酒的频率匹配;曼-惠特尼U测试用于组比较.
主要成果:
- 病例的身体质量指数高于对照组.
- 虽然平均终身体育活动水平在各组之间相似,但在体育活动总时间和OSCC风险之间发现了统计学上显著的反向关系.
- 在特定的身体活动领域 (职业,家庭,体育) 和OSCC风险之间没有观察到显著的关联.
结论:
- 终身体育活动的总持续时间可能会对口腔状细胞癌产生保护作用.
- 整体体身体活动水平和强度与OSCC风险没有显著联系.
- 需要进一步的研究来阐明身体活动和口腔癌之间的复杂关系.
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