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Updated: Jun 25, 2025

Analysis of mRNA Nuclear Export Kinetics in Mammalian Cells by Microinjection
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Analysis of mRNA Nuclear Export Kinetics in Mammalian Cells by Microinjection

Published on: December 4, 2010

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抑制mRNA核出口可以促进SARS-CoV-2的病变发生

Menghan Mei1, Anastasija Cupic2,3, Lisa Miorin2,4

  • 1Department of Biochemistry, Center for Structural Biology, Vanderbilt University School of Medicine, Nashville, TN 37232.

Proceedings of the National Academy of Sciences of the United States of America
|May 20, 2024
PubMed
概括

严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) 非结构蛋白1 (Nsp1) 使用酸性N终端补丁结合NXF1,抑制宿主mRNA输出并促进病毒毒性.

关键词:
在 NXF1 的情况下.在 Nsp1 中使用.这就是SARS-CoV-2病毒.在mRNA出口方面,mRNA出口是非常重要的.核运输运输是核运输.

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