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Updated: Jun 25, 2025

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跨剂量和配方的dolutegravir临床病毒反应的桥梁使用基于模型的暴露-反应分析在儿科

Hardik Chandasana1, Siobhán Hayes2, Ann M Buchanan3

  • 1Clinical Pharmacology Modeling & Simulation, GSK, Collegeville, Pennsylvania, USA.

AIDS (London, England)
|May 20, 2024
PubMed
概括

艾滋病毒-1感染儿童的多卢特格拉维尔 (DTG) 暴露通常高于病毒学反应所需的水平. 这支持使用成人剂量指南用于儿科DTG配方.

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