来自新罕布什尔州出生队列研究的落叶牙:牙元素的早期生活环境和饮食预测因素
Julia A Bauer1, Tracy Punshon2, Matthew N Barr3
1Department of Epidemiology, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA; Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois Chicago, Chicago, IL, USA.
Environmental research
|May 20, 2024
概括
孕产妇和婴儿的因素,包括自来水元素含量和养习惯,影响了儿童落叶牙中的元素度. 这项研究确定了牙元素沉积在关键发育阶段的关键预测因素.
科学领域:
- 环境健康 环境健康
- 儿科牙科 儿科牙科
- 毒理学 毒理学 毒理学
背景情况:
- 有限的研究存在于影响树叶牙元素度的因素.
- 了解这些预测因素对于评估早期暴露至关重要.
研究的目的:
- 调查母婴特征,怀孕期间家庭自来水元素含量,以及棚叶牙中的元素度之间的关联.
- 为了确定元素沉积在落叶牙中的预测因素.
主要方法:
- 从新罕布什尔州出生队列研究中分析了152名孕妇和婴儿对象. 新罕布什尔州出生队列研究.
- 在怀孕和婴儿时期收集饮食,社会人口统计和家庭自来水元素数据.
- 测量牙中的纵向元素沉积,使用激光除-诱导合的等离子体质谱法 (LA-ICP-MS) 和多变量线性混合模型.
主要成果:
- 在牙中测量了12种元素,包括 (Pb), (Sr), (Ba) 和 (Li).
- 在自来水中增加的Pb和Sr与在产前和产后牙中增加的Pb和Sr相关.
- 与纯母乳养相比,配方养与产后牙中的Sr,Ba和Li度较高有关.
结论:
- 龙头水元素度和婴儿养方法是牙元素水平的重要预测因素.
- 调查结果提供了对早期暴露健康结果研究中的潜在混因素的见解.
- 这项研究强调了在儿童元素暴露评估中考虑环境和养因素的重要性.
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