儿科腹部结核病的模式和结果:一个单一中心的队列研究
Susan John1, Dhruva Ghosh2, Vishal Michael3
1NIHR Health Research Unit on Global Surgery, India Hub, Christian Medical College, Ludhiana, Punjab, India.
Journal of pediatric surgery
|May 20, 2024
概括
儿童的腹结核需要高度的临床怀疑才能诊断. 肠道感染和年龄较大与死亡率的增加有关,这凸显了针对儿科腹部结核病进行有针对性的研究的需要.
科学领域:
- 儿童传染病 儿童传染病
- 胃肠病学 胃肠病学
- 全球卫生健康 全球卫生健康
背景情况:
- 胃结核病 (TB) 的诊断和治疗可能具有挑战性,特别是在儿童中.
- 有限的研究重点关注儿科腹部结核病的结果和不良事件的危险因素.
研究的目的:
- 评估治疗反应,并确定与患有腹部结核病的儿童较差结局相关的因素.
- 分析儿科腹部结核病的表现,管理和结果.
主要方法:
- 从2007年至2021年期间对75例儿科腹部结核病例进行了回顾性分析.
- 通过问卷和后续调查 (面对面或通过电话) 收集的数据.
- 评估人口特征,症状,调查,治疗和结果.
主要成果:
- 在所有结核病例中,腹部结核病发病率为7%;平均年龄为10.1岁.
- 中腔淋巴结 (67%) 和小肠 (33%) 是常见的部位.
- 高龄,小肠干扰和手术与较高的死亡率 (6/70人死亡) 有关.
结论:
- 肠道感染需要手术,并增加了儿科腹部结核病的死亡风险.
- 患有腹部结核病的青少年经历的结果较差.
- 需要对特定子组进行进一步的研究,以改善预防和治疗策略.
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