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外耳道的微生物组:长期使用助听器后的变化

Atte Sjövall¹, Ella Mustanoja², Annina Lyyski²

¹Department of Otorhinolaryngology-Head and Neck Surgery, University of Helsinki and Helsinki University Hospital.

Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology

|May 20, 2024

概括

长期使用助听器会改变耳道微生物群,减少细菌的多样性. 外耳道 (EAC) 微生物群落的这种转变可能会增加对耳部疾病的敏感性.

科学领域:

微生物学微生物学
耳鼻喉科耳鼻喉科耳鼻喉科
基因组学就是基因组学.

背景情况:

听力助听器被听力损失的人广泛使用.
外耳道 (EAC) 拥有复杂的微生物群落.
了解助听器使用对EAC微生物群的影响对于耳朵健康至关重要.

研究的目的:

调查长期使用助听器的人与非使用者之间的外部听道 (EAC) 的微生物组成.
识别因长时间使用助听器而改变的特定细菌种群.

主要方法:

一项涉及48名长期助听器使用者和59名无症状耳朵的对照者的横截面研究.
外部听道 (EAC) 样本采集使用无DNA扫描仪.
细菌群体使用16S rRNA基因安普利康序列分析.

主要成果:

与对照组相比,助听器使用者表现出明显较低的细菌多样性 (α和β多样性).
发现的最常见的细菌是耳膜杆菌 (Staphylococcus auricularis),耳膜杆菌 (Alloiococcus otitis),杆菌 (Cutibacterium acnes) 和耳膜杆菌 (Corynebacterium otitidis).这些细菌中,最常见的细菌是耳膜杆菌 (Staphylococcus auricularis),耳膜杆菌 (Alloiococcus otitis),杆菌 (Cutibacterium acnes) 和耳膜杆菌 (Corynebacterium otitidis).
助听器使用者的Corynebacterium tuberculostearicum含量较高,而像金黄色葡萄球菌 (Staphylococcus aureus) 这样的常见病原体较少.

结论:

长期使用助听器可显著减少外部听道 (EAC) 微生物群中的细菌多样性.
这些变化主要影响共生细菌,可能增加对EAC条件的敏感性.
需要进一步的研究来阐明这些微生物组变化的临床影响.

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