热应激会降低牛卵细胞的成熟和发育能力
1Department of Animal Sciences, Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University, POB 12 Rehovot, 76100, Israel.
Reproduction, fertility, and development
|May 21, 2024
概括
过热会损害卵巢毛囊和卵细胞,损害生育能力. 虽然热应激会立即造成伤害,但有些卵细胞会恢复,这表明只有某些卵泡亚群受到影响.
科学领域:
- 生殖生物学 生殖生物学
- 环境压力生理学生理学
背景情况:
- 卵巢毛囊和卵细胞对热应激很敏感.
- 暴露于热量会导致毛囊发育受损,卵细胞能力受损.
研究的目的:
- 审查热引起的卵细胞损伤的细胞和分子机制.
- 讨论热应激对卵细胞成熟,受精和胚胎发育的影响.
主要方法:
- 审查由于热应激而导致卵细胞的记录变化.
- 讨论受热暴露影响的细胞和分子通路.
主要成果:
- 热应激会损害核和细胞质成熟,线粒体功能,并诱导亡.
- 热应激的影响延伸到胚胎发育,并持续到寒冷的季节,影响生育能力.
- 卵细胞恢复表明损伤仅限于特定的卵泡亚群.
结论:
- 热应激通过各种细胞和分子机制显著影响卵细胞发育能力.
- 热应激对生育能力的有害影响是长期的,不仅仅影响了直接的生殖周期.
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