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在狗中与施密特状综合征相关的泛化大食道
Reza Azargoun1, Seyed Mohammad Hashemi-Asl2, Siamak Asri-Rezaei1
1Department of Internal Medicine and Clinical Pathology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.
概括
这种案例研究突出了一个罕见的自免疫多腺体综合征 (APS) 在一只狗,呈现与大食道. 成功治疗并发性甲状腺功能低下症,低皮质皮质症和肌痛性肌痛症,解决了大食道.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 内分泌学 在内分泌学.
- 免疫学 免疫学 免疫学
背景情况:
- 狗的超大食管可能源于各种潜在的疾病.
- 自免疫多腺综合征 (APS) 是一种罕见的,复杂的内分泌-自身免疫性疾病.
- 施密特综合征是APS的一种形式,涉及上腺功能衰竭和自身免疫性甲状腺疾病.
研究的目的:
- 报告一种独特的犬类自身免疫多腺体综合征 (APS) 病例.
- 描述成功诊断和管理一只同时患有甲状腺功能低下症,低 adrenocorticism 和 myasthenia gravis 导致大食道的狗的情况.
- 提高临床医生对兽医诊断中的APS的认识.
主要方法:
- 对大食道进行临床检查和诊断成像 (放射) 检查.
- 综合实验室分析包括血液检查,甲状腺功能测试,上腺功能测试和乙胆受体抗体度.
- 多模式治疗方法针对个体内分泌和自身免疫疾病.
主要成果:
- 一只2岁的亚洲牧羊犬被诊断出患有大食道,主要的甲状腺功能低下症,主要的缺皮质症和肌痛性脑.
- 甲状腺刺激激素的升高,甲状腺激素的降低,低皮质血量和高乙胆受体抗体水平被注意到.
- 在所有被诊断疾病的治疗后,大食道的解决得到了实现.
结论:
- 这一病例是狗体内首次记录出施密特综合征 (一种类型的APS) 的病例.
- 同时发生的自身免疫性疾病可以表现为复杂的临床症状,包括大食道.
- 识别APS对于有效治疗和改善受影响动物的结果至关重要.
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