抗疲劳和帮助睡眠的效果在含有Ganoderma lucidum提取物的不同配方之间有很大差异
Kexin Li1,2, Wenzhen Liu1, Changhui Wu3
1State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fujian Academy, University of Chinese Academy of Sciences, Fuzhou, Fujian, 350108, China.
Heliyon
|May 21, 2024
概括
这项研究表明,Ganoderma lucidum提取物可以对抗疲劳并改善睡眠. 特定配方,PGB和GBS,在小鼠中分别表现出显著的抗疲劳和帮助睡眠的效果.
科学领域:
- 菌类学 菌类学是指菌类学.
- 药理学 药理学是指药理学的学科.
- 传统中国医药 传统中国医药
背景情况:
- (Lingzhi) 是一种药用,在传统医学中使用的历史悠久.
- 其提取物以各种健康益处而闻名,包括适应性和免疫调节性质.
- 目前正在进行研究,以科学验证其针对特定健康状况的疗效,例如疲劳和睡眠障碍.
研究的目的:
- 为了研究不同Ganoderma lucidum配方的抗疲劳和促进睡眠的作用.
- 评估这些配方对与疲劳和睡眠有关的生理标记物的影响.
- 为开发基于Ganoderma lucidum的产品提供科学基础,用于疲劳和睡眠支持.
主要方法:
- 制备了两种不同的Ganoderma lucidum配方,即PGB和GBS.
- 给小鼠服用这些配方或主要成分连续14天.
- 通过举重游泳测试来评估抗疲劳,而通过测量睡眠延迟和持续时间来评估睡眠质量. 生物化学分析包括血液中的乳酸,血清尿素,肝脏和肌肉的葡萄糖原和马隆迪 (MDA) 水平.
主要成果:
- PGB配方显著增强了抗疲劳特性,延长了疲劳时间,增加了肝脏和肌肉的糖原水平,同时减少了血清乳酸,尿素和MDA.
- GBS配方显著改善了睡眠质量,缩短了睡眠延迟时间,延长了睡眠时间,并降低了肌肉MDA水平.
- 这些发现突出了基于其组成和制备的Ganoderma lucidum配方的差异性作用.
结论:
- 甘 lucidum 提取物具有独特的抗疲劳和帮助睡眠的特性,这些特性取决于配方.
- PGB配方有效地对抗身体疲劳,而GBS配方有助于改善睡眠质量.
- 这项研究支持开发基于Ganoderma lucidum的向疗法,用于治疗疲劳和睡眠障碍.
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