前列腺癌治疗模式和死亡率的差异:黑人种族与末期脏病之间的相互作用
Nagaraju Sarabu1,2, Weichuan Dong3, Siran M Koroukian3
1Division of Nephrology, Department of Medicine, The Metrohealth System, Cleveland, Ohio, USA.
Cancer medicine
|May 21, 2024
概括
患有末期脏病 (ESKD) 的黑人男性在前列腺癌治疗和死亡率方面面临着显著的种族差异. 这种并发性疾病加剧了现有的不平等现象,导致前列腺癌黑人男性的治疗结果更差.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 腎臟病學 (nephrology) 是一種醫學專業.
- 在瘤学瘤学.
背景情况:
- 黑人男性和末期脏病患者 (ESKD) 的前列腺癌结果较差.
- 研究种族和ESKD对前列腺癌治疗和死亡率的综合影响至关重要.
研究的目的:
- 检查黑人种族与末期病 (ESKD) 对前列腺癌治疗率的相互作用.
- 评估这种相互作用对前列腺癌特定死亡率的影响.
主要方法:
- 使用了监测,流行病学和最终结果-医疗保险数据 (2004-2016).
- 包括516名黑人男性和551名患有ESKD的白人男性,以及22299名黑人男性和141821名没有ESKD的白人男性 (年龄≥40岁).
- 分析了前列腺特异性抗原水平,治疗率和死亡率,根据年龄进行调整.
主要成果:
- 与没有ESKD的白人男性相比,患有ESKD的黑人男性在本地和晚期前列腺癌的治疗率最低.
- 与没有ESKD的白人男性相比,患有ESKD (局部和晚期) 的白人男性和患有ESKD (仅晚期) 的黑人男性的前列腺癌特异性死亡率更高.
- 在所有黑人男性 (有或没有ESKD) 和在诊断时患有ESKD的白人男性中观察到高的前列腺特异性抗原水平.
结论:
- 末期病 (ESKD) 增加了黑人男性前列腺癌治疗中的种族差异的脆弱性.
- 乳腺癌在前列腺癌发病率方面加剧了现有的种族不平等现象,尤其是在晚期的死亡率方面.
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