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Updated: Jun 25, 2025

Enrich and Expand Rare Antigen-specific T Cells with Magnetic Nanoparticles
09:28

Enrich and Expand Rare Antigen-specific T Cells with Magnetic Nanoparticles

Published on: November 17, 2018

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整合强化学习和蒙特卡洛树寻找增强的新抗原疫苗设计

Yicheng Lin1,2, Jiakang Ma1,2, Haozhe Yuan1,2

  • 1MOE Key Laboratory of Metabolism and Molecular Medicine, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences and Shanghai Xuhui Central Hospital, Fudan University, 131 DongAn Road, Shanghai, 200032, China.

Briefings in bioinformatics
|May 21, 2024
PubMed
概括

一个新的算法UltraMutate通过发现与人类白细胞抗原 (HLA) 分子结合更强的突变来增强新抗原疫苗设计. 这种方法提高了癌症免疫治疗中强大的适应性免疫反应的潜力.

关键词:
蒙特卡罗树搜索 蒙特卡罗树搜索强化学习是一种强化学习.人类白细胞抗原.主要的组织相容性复杂.新抗原疫苗设计

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Simultaneous Quantification of Anti-vector and Anti-transgene-Specific CD8+ T Cells Via MHC I Tetramer Staining After Vaccination with a Viral Vector08:10

Simultaneous Quantification of Anti-vector and Anti-transgene-Specific CD8+ T Cells Via MHC I Tetramer Staining After Vaccination with a Viral Vector

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