根据风险调整的抗生素日的计算和反作为全州创伤协作中的过程措施
Naveen F Sangji1,2,3, Jacob M Dougherty1,2, Christopher J Tignanelli4,5
1Department of Surgery, University of Michigan, Ann Arbor, MI, USA.
The American surgeon
|May 21, 2024
概括
创伤中心在使用抗生素的持续时间中显示出显著的差异. 这项研究开发了一种比较抗生素日的方法,揭示了医院之间更好的抗生素管理方面的差异.
科学领域:
- 创伤护理 创伤护理
- 传染性疾病 传染性疾病
- 医疗保健服务研究 医疗服务研究
背景情况:
- 抗生素管理对于优化创伤护理的治疗和资源利用至关重要.
- 目前用于识别感染并发症的方法无法量化用于治疗的资源.
- 需要一种新的方法来对创伤医院的抗生素使用时间进行基准测试.
研究的目的:
- 开发和验证一种方法来对创伤中心的抗生素使用时间进行基准测试.
- 为了考虑抗生素使用的可能性及其持续时间.
- 在创伤设施中识别风险调整的抗生素日数的变化.
主要方法:
- 使用后勤回归和负二项式分布的两部分模型应用于35个创伤中心 (2020-2023) 的数据.
- 该模型根据受伤严重程度,感染类型,并发症和并发症进行调整.
- 计算了观察到预期的比率和置信区间,以确定异常中心.
主要成果:
- 平均抗生素治疗持续时间为1.98天,但观察到很大差异 (0.76至2.69天).
- 总共分析了88403个治疗日.
- 在抗生素使用方面,有9个中心被确定为低异常值,6个中心被确定为高异常值.
结论:
- 在创伤中心之间,风险调整后的抗生素使用时间存在显著差异.
- 需要进一步的研究来了解这种变化的驱动因素.
- 这些发现支持需要在创伤护理中改进抗生素管理策略.
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