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合成,表征,抗微生物和在基研究的伊萨丁希夫基链接1,2,3-三醇混合物

Vijay Kumar1, Akanksha Bhukal1, Anirudh Pratap Singh Raman2

  • 1Department of Chemistry, Guru Jambheshwar University of Science & Technology, Hisar, Haryana, 125001, India.

Chemistry & biodiversity
|May 21, 2024
PubMed
概括

新的伊萨-希夫基结合的1,2,3-三混合物显示出强大的抗菌活性. 化合物5j具有显著的抗菌和抗真菌作用,通过分子对接和动力学研究得到验证.

关键词:
1,2,3-三醇杂交的混合物抗微生物活性 抗微生物活性停靠的对接方式异氨酸 是一种异氨酸.分子动力学分子动力学这里是船只基地.

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The reaction of weakly electrophilic aryldiazonium (also called arenediazonium) salts with highly activated aromatic compounds leads to the formation of products with an —N=N— link, called an azo linkage. This reaction, presented in Figure 1, is known as diazo coupling and occurs without the loss of the nitrogen atoms of the aryldiazonium salt. Highly activated aromatic compounds such as phenols or arylamines favor the diazo coupling reaction. The coupling generally occurs at the...
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