在与大脑内皮细胞相互作用时,B组菌转录基因组

Nadine Vollmuth1, Bailey E Bridgers1, Madelyn L Armstrong1

  • 1Department of Biological Sciences, University of Alabama, Tuscaloosa, Alabama, USA.

PubMed
概括

乙组链球菌 (GBS) 脑膜炎是新生儿脑膜炎的主要原因. RNA-seq分析确定了GBS毒性因子,其中一个关键的调节器codY被降低,导致细菌粘附度增加和入侵大脑内皮细胞.

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