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IL-22 调节肠道上皮细胞中MASTL的表达

Kristina Pravoverov1,2, Iram Fatima2, Susmita Barman2

  • 1Eppley Institute, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska, United States.

American journal of physiology. Gastrointestinal and liver physiology
|May 21, 2024
PubMed
概括

在结肠炎相关的癌症中,微管相关的血清三氨酸激酶类 (MASTL) 通过介质蛋白-22 (IL-22) 上调调节. 这种IL-22/AKT信号通路通过碳酸酶IX (CAIX) 增加了MASTL的稳定性,促进了细胞的存活和增殖.

关键词:
碳酸无水酶9 (CA9或CAIX) 的使用大肠炎是一种大肠炎.大肠炎相关的癌症 (CAC)干白素22 (IL-22) 是一种干白素.微管相关的氨酸-氨酸激酶类 (MASTL)

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