患有先天性肺异常的儿童下呼吸道感染
Louis Dossche1, Casper Kersten1, Joost van Rosmalen2,3
1Department of Pediatric Surgery, Erasmus MC Sophia Children's Hospital, Rotterdam, The Netherlands.
Pediatric pulmonology
|May 21, 2024
概括
患有先天性肺部异常 (CLA) 的儿童经过手术或观察管理,具有类似的下呼吸道感染 (LRTI) 率. 手术显著降低了CLA患者的LRTI发病率.
科学领域:
- 儿科肺病学 儿科肺病学
- 胸部外科手术 胸部外科手术
- 遗传异常 是一种先天性异常.
背景情况:
- 先天性肺部异常 (CLA) 是影响肺部发育的一系列疾病.
- 下呼吸道感染 (LRTI) 是患有CLA的儿童常见的并发症.
- 对CLA的管理策略范围从观察到手术切除.
研究的目的:
- 为了比较患有CLA的儿童的LRTI发病率,手术治疗与观察治疗相比.
- 评估手术切除对CLA患者LRTI发病率的影响.
主要方法:
- 对患有CLA的儿童进行回顾性队列研究 (1999-2021).
- 手术和观察管理组之间的LRTI发病率的比较.
- 对手术治疗患者的切割前和切割后LRTI发病率的分析.
主要成果:
- 在整个童年期间,手术组和观察组之间LRTI发病率没有显著差异.
- 接受CLA手术的儿童在切除前与切除后相比,LRTI率显著更高 (IRR3.57).
结论:
- 与观察相比,CLA的外科治疗似乎没有改变LRTI总体发病率.
- 手术切除CLA与LRTI发病率的显著降低有关.
- 多学科讨论和诊断成像对于决定CLA的手术干预至关重要.
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