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相关概念视频

Phylogeny01:23

Phylogeny

43.9K
Phylogeny is concerned with the evolutionary diversification of organisms or groups of organisms. A group of organisms with a name is called a taxon (singular). Taxa (plural) can span different levels of the evolutionary hierarchy. For instance, the group containing all birds is a taxon (comprising the class Aves), and the group of all species of daisies (the genus Bellis) is a taxon. Phylogenies can likewise include just one genus (i.e., depict species relationships) or span an entire kingdom.
43.9K
Phylogenetic Trees03:21

Phylogenetic Trees

45.3K
Phylogenetic trees come in many forms. It matters in which sequence the organisms are arranged from the bottom to the top of the tree, but the branches can rotate at their nodes without altering the information. The lines connecting individual nodes can be straight, angled, or even curved.
45.3K
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

5.7K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
5.7K
Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

7.1K
The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
7.1K
Speciation Rates01:07

Speciation Rates

21.2K
Overview
21.2K
Multi-species Conserved Sequences02:51

Multi-species Conserved Sequences

3.9K
Next-generation sequencing technologies have created large genomic databases of a variety of animals and plants. Ever since the human genome project was completed, scientists studied the genome of primates, mammals, and other phylogenetically distant living beings. Such large-scale  studies have provided new insights into the evolutionary relationship between organisms.
Although the genome of each species varies greatly from each other, a few sequences are highly conserved. Such conserved...
3.9K

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相关实验视频

Updated: Jun 25, 2025

A Practical Guide to Phylogenetics for Nonexperts
12:00

A Practical Guide to Phylogenetics for Nonexperts

Published on: February 5, 2014

35.3K

顺序的贝叶斯斯系遗传推理.

Sebastian Höhna1,2, Allison Y Hsiang1,2

  • 1GeoBio-Center LMU, Ludwig-Maximilians-Universität München, Richard-Wagner Str. 10, 80333 Munich, Germany.

Systematic biology
|May 21, 2024
PubMed
概括
此摘要是机器生成的。

我们开发了一种序列的贝叶斯氏系遗传推断方法,使用重要性抽样来在分析步骤之间传播不确定性. 与传统方法相比,这种方法提高了准确性和灵活性,特别是当测试多个模型来估计分歧时间时.

关键词:
贝叶斯的推理 贝叶斯的推理这就是RevBayes.差异时间估计差异时间估计.关节后部分布 关节后部分布参数不确定性参数不确定性人类遗传学 遗传学

更多相关视频

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin
08:57

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin

Published on: August 14, 2018

15.9K
Creating and Applying a Reference to Facilitate the Discussion and Classification of Proteins in a Diverse Group
07:49

Creating and Applying a Reference to Facilitate the Discussion and Classification of Proteins in a Diverse Group

Published on: August 16, 2017

7.1K

相关实验视频

Last Updated: Jun 25, 2025

A Practical Guide to Phylogenetics for Nonexperts
12:00

A Practical Guide to Phylogenetics for Nonexperts

Published on: February 5, 2014

35.3K
Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin
08:57

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin

Published on: August 14, 2018

15.9K
Creating and Applying a Reference to Facilitate the Discussion and Classification of Proteins in a Diverse Group
07:49

Creating and Applying a Reference to Facilitate the Discussion and Classification of Proteins in a Diverse Group

Published on: August 16, 2017

7.1K

科学领域:

  • 计算生物学 计算生物学
  • 进化生物学 进化生物学
  • 生物信息学是一种生物信息学.

背景情况:

  • 贝叶斯系遗传学推理理想情况下使用联合层次模型,但在计算上昂贵.
  • 目前的管道使用顺序分析与点估计,未能传播不确定性.
  • 这种缺乏不确定性传播可以导致不准确的结果和过度自信.

研究的目的:

  • 开发和测试贝叶斯系遗传学的顺序推理方法.
  • 为了考虑到分析步骤之间的不确定性,并提高软件和模型选择的灵活性.
  • 为联合推理提供一个计算效率高的替代方案,特别是用于测试多个模型.

主要方法:

  • 使用重要性抽样进行顺序推理方法的正式开发.
  • 从前一步的后部分布生成用于后续分析的观察结果.
  • 用玩具示例和昆虫分歧时间估计的经验案例研究来测试方法.

主要成果:

  • 顺序方法可以解释不确定性,并提供更大的软件灵活性.
  • 在测试多个模型时,它在计算上比联合推理更有效.
  • 该方法准确地反映了具有足够数据或样本的联合推断;点估计可能有偏见.

结论:

  • 序列贝叶斯系遗传推理提供了一个强大而灵活的框架.
  • 它可以有效地测试各种差异时间估计策略.
  • 该方法准确地估计了后部分布,改进了家族遗传学分析.