仅仅是2019年新冠肺炎病史是否会增加手术后术后肺部并发症的风险? 使用血清学评估进行前性观察性研究
Ah Ran Oh1, Eun-Suk Kang2, Jungchan Park1
1Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
PloS one
|May 21, 2024
概括
患有2019年新冠病毒病 (COVID-19) 轻度病史的患者不会面临术后肺部并发症的风险增加. 这一发现表明,对于这些接受手术的人来说,可能不需要额外的预防措施.
科学领域:
- 麻醉学和重症监护医学
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
背景情况:
- 人们越来越担心手术后肺部并发症 (PPC) 在患有2019年新冠肺炎 (COVID-19) 病史的患者中增加.
- 需要澄清COVID-19病史对手术结果带来的实际风险.
研究的目的:
- 为了前性地比较患有和没有COVID-19病史,接受重大非心脏手术的患者中PPC的发病率.
- 为了确定以前的COVID-19感染是否会影响患上术后肺部并发症的风险.
主要方法:
- 一项前性观察性研究,涉及200名接受重大非心脏手术的成年患者,分为COVID-19病史和没有COVID-19病史组.
- 对SARS-CoV-2免疫球蛋白G进行血清检测,以在没有确诊的COVID-19病史的患者中识别以前未被诊断的感染.
- PPC的复合发病率的比较,包括,多叶膜溢出,肺,肺炎,吸入性肺炎和补充氧气的需要.
主要成果:
- 在有或没有COVID-19病史的患者之间没有观察到PPC风险的显著差异 (24.0%与26.0%,P=0.92).
- 在没有先前确诊的诊断的情况下被确定为血清阳性患者中,PPC的发病率也相似.
- 所有患有COVID-19病史的患者在感染期间报告了轻度或没有症状.
结论:
- 轻度或无症状的COVID-19病史似乎不会增加术后肺部并发症的风险.
- 目前的证据表明,对于有轻度COVID-19病史的患者,可能不需要采取预防PPC的特定额外预防措施.
- 进一步的研究可能是有必要的,以调查在特定的患者小组中潜在的长期呼吸道影响.
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