美国成年人中饮食总黄酸和甲状腺功能之间的关系,NHANES 2007-2010年
Jie Wu1, Chuyu Jia2, Zirui Zhang1,3
1Department of Thyroid Surgery, Shanxi Provincial People's Hospital, Taiyuan, Shanxi, China.
PloS one
|May 21, 2024
概括
较高的饮食总类黄酸 (TFs) 摄入量与较低的总甲状腺素 (TT4) 水平有关. 这种关联在高收入和贫困与收入比率较高的人群中更为强烈,并且与自由三甲状腺素 (FT3) 发现了U形链接.
科学领域:
- 营养科学 营养科学
- 内分泌学 在内分泌学.
- 流行病学 流行病学
背景情况:
- 有限的流行病学数据存在于饮食总黄素 (TFs) 和甲状腺功能.
- 之前的小型研究表明,黄类药物对甲状腺疾病有影响.
研究的目的:
- 为了研究饮食中的TFs与成年人血清甲状腺功能之间的关系.
- 探索潜在的非线性关联和子组差异.
主要方法:
- 来自NHANES 2007-2010数据集的4949名成年人的分析.
- 使用多变量线性回归,子组分析和受限立方线 (RCS).
主要成果:
- 饮食中的TFs摄入与总甲状腺素 (TT4) 有负相关性.
- 在高收入和高贫困与收入比率的群体中,协会更强.
- 在TFs摄入量和自由三甲状腺素 (FT3) 之间观察到U形关系.
结论:
- 较高的饮食TF摄入量与较低的TT4水平有关.
- 饮食中的TF摄入量可能会影响甲状腺功能,特别是在特定的社会经济群体.
- 研究结果表明,TF摄入可能是甲状腺功能障碍管理的一个因素.
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