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Updated: Jun 25, 2025

Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation
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载复合物的双重作用是MHC-I呈现的校对者和限制者

Jamina Brunnberg1, Martina Barends1, Stefan Frühschulz1

  • 1Institute of Biochemistry, Biocenter, Goethe University Frankfurt, Frankfurt am Main 60438, Germany.

Proceedings of the National Academy of Sciences of the United States of America
|May 21, 2024
PubMed
概括

载复合体 (PLC) 编辑模块组件,如塔帕辛,限制丰富的和校对-MHC-I (pMHC-I) 复合体,确保免疫监控的多样化抗原呈现.

关键词:
T细胞受体受体的 T 细胞受体.处理抗原处理.酸载荷复杂的复合物.与抗原处理TAP相关的载体.与瘤相关的抗原.

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