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Updated: Jun 25, 2025

Peptide-based Identification of Functional Motifs and their Binding Partners
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Peptide-based Identification of Functional Motifs and their Binding Partners

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可逆反应性亲和选择-质谱学可识别共价结合物

Peiyuan Zhang1, Xiyun Ye1, John C K Wang2

  • 1Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.

Journal of the American Chemical Society
|May 21, 2024
PubMed
概括

研究人员开发了ReAct-ASMS,这是一种用于识别共价结合物的新平台. 这种方法使用可逆化学和质谱法来寻找治疗开发的向抑制剂.

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Peptide Identification Using Tandem Mass Spectrometry01:33

Peptide Identification Using Tandem Mass Spectrometry

Tandem mass spectrometry, also known as MS/MS or MS2, is an analytical technique that employs two mass analyzers. Essentially it is a series of mass spectrometers that helps isolate a particular biomolecule and then helps study its chemical properties.
This technique helps gather information regarding the protein from which the peptide was obtained and to study the peptides’ amino acid sequence. Identifying peptides from a complex mixture is an important component of the growing field of...
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