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面向用于高能电子放射治疗的多层微结构探测器

Davide Brivio^1,2, Arianna Liles^1,3, Matthew Gagne^3,4

¹Brigham and Women's Hospital, Boston, Massachusetts, USA.

Medical physics

|May 21, 2024

概括

这项研究引入了一种用于电子束剂量计的新型气凝高能电流 (HEC) 探测器. 在超高剂量率放射疗法 (FLASH) 和非常高能电子 (VHEE) 应用中,HEC探测器显示出前景.

科学领域:

医学物理医学物理
放射治疗技术放射治疗技术
辐射检测辐射检测辐射检测

背景情况:

在放射治疗中电子束应用的复兴,包括超高剂量速率 (FLASH) 和非常高能电子 (VHEE),需要先进的电子束监测和剂量测量技术.
这些先进的电子束技术的临床转化取决于开发新的,可靠的剂量测量方法.

研究的目的:

研究多层纳米孔气凝高能电流 (HEC) 探测器作为电子束剂量计的潜力.
评估探测器适用于非常高剂量率应用的适用性,评估其对辐射损伤和信号和的抗性.
通过实验和计算方法探索探测器对不同电子能量和残余范围的反应,为FLASH和VHEE应用建立基线.

主要方法:

使用不同层厚度 (10-70μm) 的 (Al),气凝 (A) 和 (Ta) 模块构建多层HEC探测器.
来自3-21个电极的信号采集,外部电压偏差为零,测量为水等效塑料中的深度函数.
使用Varian TrueBeam进行6,9,12和15 MeV的能量电子束辐射.
使用CEPXS/ONEDANT的1D确定性代码对相同的探测器几何进行计算模拟.
在水中使用二极管测量百分比深度剂量 (PDD(z)) 来分析不同能量和残留范围的HEC探测器响应.

主要成果:

从Ta电极测量的电流反映了水中的能量沉积模式,与临床PDD的导数相关,对光子污染进行了校正.
来自Ta电极的信号呈现出正面值,深度下降到R50的负最小值,并在实际范围 (Rp) 附近返回零.
Al电极产生了一个类似于电子 PDD (z) 的信号,但其表面信号减少,并增加了制动辐射尾部.
从Ta和Al电极中减去信号,得到了更正的PDD (z,E) 曲线,考虑了制动辐射污染.

结论:

多层HEC传感器对电子束具有独特的响应特性,与传统的离子室或二极管不同.
传感器对电子不平衡的敏感性使高Z电极能够提供与电荷沉积成比例的信号.
观察到的信号模式可以有效地使用百分比深度剂量 (PDD(z)) 的导数进行建模.

关键词:

梁监测梁监测梁监测梁监测剂量测量方法剂量测量方法一个电子束的电子束.

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